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As indicated in a meta-analysis of MTHFR consisted of 7 studies, individuals carried with TT homozygotes had the greatest risk of schizophrenia, compared to the subjects with CC wild type and CT heterozygous genotypes 44

Furthermore, this excess serotonin could eventually lead to dysregulation of its production (435)

504 Taken together, these findings highlight the broader relevance of cholesterol metabolism in immune regulation

10 Treatment options include loop diuretics, RAASi dose modification, identification and removal of hyperkalemia-causing medications, and potassium binders